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Therapeutic Landscape of Malignant Pleural Mesothelioma: Collateral Vulnerabilities and Evolutionary Dependencies in the Spotlight

Malignant pleural mesothelioma (MPM) is the epitome of a recalcitrant cancer driven by pharmacologically intractable tumor suppressor proteins. A significant but largely unmet challenge in the field is the translation of genetic information on alterations in tumor suppressor genes (TSGs) into effect...

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Publicado en:Front Oncol
Autores principales: Xu, Duo, Yang, Haitang, Schmid, Ralph A., Peng, Ren-Wang
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7538645/
https://ncbi.nlm.nih.gov/pubmed/33072611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.579464
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