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Endoplasmic Reticulum Stress Signaling as a Therapeutic Target in Malignant Pleural Mesothelioma

Malignant pleural mesothelioma (MPM) is a lethal cancer with limited treatment options. No targeted therapy has emerged yet. Here, we performed an integrated molecular characterization of patient tumors in the TCGA dataset, and discovered that endoplasmic reticulum (ER) stress and the adaptive unfol...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Xu, Duo, Yang, Haitang, Yang, Zhang, Berezowska, Sabina, Gao, Yanyun, Liang, Shun-Qing, Marti, Thomas M., Hall, Sean R. R., Dorn, Patrick, Kocher, Gregor J., Schmid, Ralph A., Peng, Ren-Wang
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6827154/
https://ncbi.nlm.nih.gov/pubmed/31597321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11101502
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