ATR is required to complete meiotic recombination in mice

Precise execution of recombination during meiosis is essential for forming chromosomally-balanced gametes. Meiotic recombination initiates with the formation and resection of DNA double-strand breaks (DSBs). Cellular responses to meiotic DSBs are critical for efficient repair and quality control, bu...

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Udgivet i:Nat Commun
Main Authors: Pacheco, Sarai, Maldonado-Linares, Andros, Marcet-Ortega, Marina, Rojas, Cristina, Martínez-Marchal, Ana, Fuentes-Lazaro, Judit, Lange, Julian, Jasin, Maria, Keeney, Scott, Fernández-Capetillo, Oscar, Garcia-Caldés, Montserrat, Roig, Ignasi
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6033890/
https://ncbi.nlm.nih.gov/pubmed/29977027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04851-z
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