ATR is a multifunctional regulator of male mouse meiosis

Meiotic cells undergo genetic exchange between homologs through programmed DNA double-strand break (DSB) formation, recombination and synapsis. In mice, the DNA damage-regulated phosphatidylinositol-3-kinase-like kinase (PIKK) ATM regulates all of these processes. However, the meiotic functions of t...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Widger, Alexander, Mahadevaiah, Shantha K., Lange, Julian, ElInati, Elias, Zohren, Jasmin, Hirota, Takayuki, Pacheco, Sarai, Maldonado-Linares, Andros, Stanzione, Marcello, Ojarikre, Obah, Maciulyte, Valdone, de Rooij, Dirk G., Tóth, Attila, Roig, Ignasi, Keeney, Scott, Turner, James M.A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6033951/
https://ncbi.nlm.nih.gov/pubmed/29976923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04850-0
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