The expression of Y-linked Zfy2 in XY mouse oocytes leads to frequent meiosis 2 defects, a high incidence of subsequent early cleavage stage arrest and infertility

Outbred XY(Sry-) female mice that lack Sry due to the 11 kb deletion Sry(dl1Rlb) have very limited fertility. However, five lines of outbred XY(d) females with Y chromosome deletions Y(Del(Y)1Ct)-Y(Del(Y)5Ct) that deplete the Rbmy gene cluster and repress Sry transcription were found to be of good f...

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Detalhes bibliográficos
Main Authors: Vernet, Nadège, Szot, Maria, Mahadevaiah, Shantha K., Ellis, Peter J. I., Decarpentrie, Fanny, Ojarikre, Obah A., Rattigan, Áine, Taketo, Teruko, Burgoyne, Paul S.
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2014
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3912830/
https://ncbi.nlm.nih.gov/pubmed/24496622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.091165
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