SETDB1 Links the Meiotic DNA Damage Response to Sex Chromosome Silencing in Mice

Meiotic synapsis and recombination ensure correct homologous segregation and genetic diversity. Asynapsed homologs are transcriptionally inactivated by meiotic silencing, which serves a surveillance function and in males drives meiotic sex chromosome inactivation. Silencing depends on the DNA damage...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Dev Cell
Päätekijät: Hirota, Takayuki, Blakeley, Paul, Sangrithi, Mahesh N., Mahadevaiah, Shantha K., Encheva, Vesela, Snijders, Ambrosius P., ElInati, Elias, Ojarikre, Obah A., de Rooij, Dirk G., Niakan, Kathy K., Turner, James M.A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Cell Press 2018
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286383/
https://ncbi.nlm.nih.gov/pubmed/30393076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2018.10.004
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