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SETDB1 Links the Meiotic DNA Damage Response to Sex Chromosome Silencing in Mice
Meiotic synapsis and recombination ensure correct homologous segregation and genetic diversity. Asynapsed homologs are transcriptionally inactivated by meiotic silencing, which serves a surveillance function and in males drives meiotic sex chromosome inactivation. Silencing depends on the DNA damage...
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| Yayımlandı: | Dev Cell |
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| Asıl Yazarlar: | , , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Cell Press
2018
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6286383/ https://ncbi.nlm.nih.gov/pubmed/30393076 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2018.10.004 |
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