The ATM Signaling Cascade Promotes Recombination-Dependent Pachytene Arrest in Mouse Spermatocytes

Most mutations that compromise meiotic recombination or synapsis in mouse spermatocytes result in arrest and apoptosis at the pachytene stage of the first meiotic prophase. Two main mechanisms are thought to trigger arrest: one independent of the double-strand breaks (DSBs) that initiate meiotic rec...

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Bibliografiska uppgifter
I publikationen:PLoS Genet
Huvudupphovsmän: Pacheco, Sarai, Marcet-Ortega, Marina, Lange, Julian, Jasin, Maria, Keeney, Scott, Roig, Ignasi
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2015
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358828/
https://ncbi.nlm.nih.gov/pubmed/25768017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005017
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