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Homeostatic control of recombination is implemented progressively in mouse meiosis

Humans suffer from high rates of fetal aneuploidy, often arising from the absence of meiotic crossover recombination between homologous chromosomes(1). Meiotic recombination is initiated by double-strand breaks (DSBs) generated by the SPO11 transesterase(2). In yeast and worms, at least one bufferin...

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Detalles Bibliográficos
Main Authors: Cole, Francesca, Kauppi, Liisa, Lange, Julian, Roig, Ignasi, Wang, Raymond, Keeney, Scott, Jasin, Maria
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3319518/
https://ncbi.nlm.nih.gov/pubmed/22388890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2451
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