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The tricky path to recombining X and Y chromosomes in meiosis

Sex chromosomes are the Achilles heel of male meiosis in mammals.(1) Mis-segregation of the X and Y chromosomes leads to sex chromosome aneuploidies, with clinical outcomes such as infertility and Klinefelter syndrome.(2) Successful meiotic divisions require that all chromosomes find their homologou...

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Détails bibliographiques
Auteurs principaux: Kauppi, Liisa, Jasin, Maria, Keeney, Scott
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3631422/
https://ncbi.nlm.nih.gov/pubmed/22954211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1749-6632.2012.06593.x
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