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Autophosphorylation of the carboxyl‐terminal domain is not required for oncogenic transformation by lung‐cancer derived EGFR mutants

Aberrant activation of cancer‐derived mutants of the epidermal growth factor receptor (EGFR) is closely associated with cancer pathogenesis and is thought to be mediated through multiple tyrosine phosphorylations within the C‐terminal domain. Here, we examined the consequences of the loss of these C...

詳細記述

保存先:
書誌詳細
出版年:Int J Cancer
主要な著者: Cho, Jeonghee, Kim, Sujin, Du, Jinyan, Meyerson, Matthew
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6033109/
https://ncbi.nlm.nih.gov/pubmed/29464683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.31332
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