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Lifespan analysis of brain development, gene expression and behavioral phenotypes in the Ts1Cje, Ts65Dn and Dp(16)1/Yey mouse models of Down syndrome

Down syndrome (DS) results from triplication of human chromosome 21. Neuropathological hallmarks of DS include atypical central nervous system development that manifests prenatally and extends throughout life. As a result, individuals with DS exhibit cognitive and motor deficits, and have delays in...

詳細記述

保存先:
書誌詳細
出版年:Dis Model Mech
主要な著者: Aziz, Nadine M., Guedj, Faycal, Pennings, Jeroen L. A., Olmos-Serrano, Jose Luis, Siegel, Ashley, Haydar, Tarik F., Bianchi, Diana W.
フォーマット: Artigo
言語:Inglês
出版事項: The Company of Biologists Ltd 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6031353/
https://ncbi.nlm.nih.gov/pubmed/29716957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.031013
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