Učitavanje...
Pathways of Metabolite-related Damage to A Synthetic p53 Gene Exon 7 Oligonucleotide using Magnetic Enzyme Bioreactor Beads and LC-MS/MS Sequencing
Reactive metabolites of environmental chemicals and drugs can cause site-specific damage to p53 tumor suppressor gene in a major pathway for genotoxicity. We report here a high throughput, cell-free, 96-well plate magnetic bead-enzyme system interfaced with LCMS/MS sequencing to bioactivate test che...
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| Izdano u: | Biochemistry |
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| Glavni autori: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2018
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6030469/ https://ncbi.nlm.nih.gov/pubmed/29750510 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b00271 |
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