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Characterizing Protein Modifications by Reactive Metabolites using Magnetic Bead Bioreactors and LC-MS/MS
We report here label-free metabolite-protein adduct detection and identification employing magnetic beads coated with metabolic enzymes as bioreactors to generate metabolites and possible metabolite-protein adducts for analysis by liquid chromatography-tandem mass spectrometry.
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| Publicat a: | Chem Commun (Camb) |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4348200/ https://ncbi.nlm.nih.gov/pubmed/25693065 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5cc00420a |
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