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Characterizing Protein Modifications by Reactive Metabolites using Magnetic Bead Bioreactors and LC-MS/MS

We report here label-free metabolite-protein adduct detection and identification employing magnetic beads coated with metabolic enzymes as bioreactors to generate metabolites and possible metabolite-protein adducts for analysis by liquid chromatography-tandem mass spectrometry.

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書誌詳細
出版年:Chem Commun (Camb)
主要な著者: Li, Dandan, Fu, You-Jun, Rusling, James F.
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4348200/
https://ncbi.nlm.nih.gov/pubmed/25693065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5cc00420a
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