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Hemopexin Increases the Neurotoxicity of Hemoglobin When Haptoglobin is Absent

Hemopexin (Hpx) binds heme with extraordinary affinity, and after haptoglobin may provide a second line of defense against the toxicity of extracellular hemoglobin (Hb). In this series of experiments, the hypothesis that Hpx protects neurons from Hb neurotoxicity was evaluated in murine primary cult...

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Dades bibliogràfiques
Publicat a:J Neurochem
Autors principals: Chen-Roetling, Jing, Ma, Sheng-Kai, Cao, Yang, Shah, Aishwarya, Regan, Raymond F.
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6030465/
https://ncbi.nlm.nih.gov/pubmed/29500821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.14328
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