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Hemopexin Increases the Neurotoxicity of Hemoglobin When Haptoglobin is Absent

Hemopexin (Hpx) binds heme with extraordinary affinity, and after haptoglobin may provide a second line of defense against the toxicity of extracellular hemoglobin (Hb). In this series of experiments, the hypothesis that Hpx protects neurons from Hb neurotoxicity was evaluated in murine primary cult...

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Detalhes bibliográficos
Publicado no:J Neurochem
Main Authors: Chen-Roetling, Jing, Ma, Sheng-Kai, Cao, Yang, Shah, Aishwarya, Regan, Raymond F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6030465/
https://ncbi.nlm.nih.gov/pubmed/29500821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.14328
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