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Haptoglobin Increases the Vulnerability of CD163-Expressing Neurons to Hemoglobin

Haptoglobin (Hp) binds hemoglobin (Hb) with high affinity and provides the primary defense against its toxicity after intravascular hemolysis. Neurons are exposed to extracellular Hb after CNS hemorrhage, and a therapeutic effect of Hp via Hb sequestration has been hypothesized. In the present study...

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Detaylı Bibliyografya
Yayımlandı:J Neurochem
Asıl Yazarlar: Chen-Roetling, Jing, Regan, Raymond F.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5304903/
https://ncbi.nlm.nih.gov/pubmed/27364920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13720
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