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Haptoglobin Increases the Vulnerability of CD163-Expressing Neurons to Hemoglobin
Haptoglobin (Hp) binds hemoglobin (Hb) with high affinity and provides the primary defense against its toxicity after intravascular hemolysis. Neurons are exposed to extracellular Hb after CNS hemorrhage, and a therapeutic effect of Hp via Hb sequestration has been hypothesized. In the present study...
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| Publicado no: | J Neurochem |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5304903/ https://ncbi.nlm.nih.gov/pubmed/27364920 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13720 |
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