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Centrosome amplification arises before neoplasia and increases upon p53 loss in tumorigenesis
Centrosome abnormalities are a typical hallmark of human cancers. However, the origin and dynamics of such abnormalities in human cancer are not known. In this study, we examined centrosomes in Barrett’s esophagus tumorigenesis, a well-characterized multistep pathway of progression, from the premali...
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| Publicado no: | J Cell Biol |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Rockefeller University Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6028540/ https://ncbi.nlm.nih.gov/pubmed/29739803 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201711191 |
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