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Patterns of selection against centrosome amplification in human cell lines
The presence of extra centrioles, termed centrosome amplification, is a hallmark of cancer. The distribution of centriole numbers within a cancer cell population appears to be at an equilibrium maintained by centriole overproduction and selection, reminiscent of mutation-selection balance. It is unk...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | PLoS Comput Biol |
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| Κύριοι συγγραφείς: | , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Public Library of Science
2021
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8143425/ https://ncbi.nlm.nih.gov/pubmed/33979341 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008765 |
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