A20 and ABIN-1 synergistically preserve intestinal epithelial cell survival

A20 (TNFAIP3) and ABIN-1 (TNIP1) are candidate susceptibility genes for inflammatory bowel disease and other autoimmune or inflammatory diseases, but it is unclear how these proteins interact in vivo to prevent disease. Here we show that intestinal epithelial cell (IEC)-specific deletion of either A...

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Veröffentlicht in:J Exp Med
Hauptverfasser: Kattah, Michael G., Shao, Ling, Rosli, Yenny Y., Shimizu, Hiromichi, Whang, Michael I., Advincula, Rommel, Achacoso, Philip, Shah, Sanjana, Duong, Bao H., Onizawa, Michio, Tanbun, Priscilia, Malynn, Barbara A., Ma, Averil
Format: Artigo
Sprache:Inglês
Veröffentlicht: Rockefeller University Press 2018
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028510/
https://ncbi.nlm.nih.gov/pubmed/29930103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20180198
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