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ABIN-1 is a Ubiquitin Sensor that Restricts Cell Death and Sustains Embryonic Development

Proteins that directly regulate TNFR signaling play critical roles in regulating cellular activation and survival. A20 Binding and Inhibitor of NFkB (ABIN-1) is a novel protein that is thought to inhibit NFkB signaling (1, 2). Here we show that mice deficient for ABIN-1 die during embryogenesis with...

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Detalhes bibliográficos
Main Authors: Oshima, Shigeru, Turer, Emre E., Callahan, Joseph A., Chai, Sophia, Advincula, Rommel, Barrera, Julio, Shifrin, Nataliya, Lee, Bettina, Yen, Benjamin, Woo, Tammy, Malynn, Barbara A., Ma, Averil
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2642523/
https://ncbi.nlm.nih.gov/pubmed/19060883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07575
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