ABIN-1 is a Ubiquitin Sensor that Restricts Cell Death and Sustains Embryonic Development

Proteins that directly regulate TNFR signaling play critical roles in regulating cellular activation and survival. A20 Binding and Inhibitor of NFkB (ABIN-1) is a novel protein that is thought to inhibit NFkB signaling (1, 2). Here we show that mice deficient for ABIN-1 die during embryogenesis with...

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Auteurs principaux: Oshima, Shigeru, Turer, Emre E., Callahan, Joseph A., Chai, Sophia, Advincula, Rommel, Barrera, Julio, Shifrin, Nataliya, Lee, Bettina, Yen, Benjamin, Woo, Tammy, Malynn, Barbara A., Ma, Averil
Format: Artigo
Langue:Inglês
Publié: 2008
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2642523/
https://ncbi.nlm.nih.gov/pubmed/19060883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07575
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