A20 and ABIN-1 synergistically preserve intestinal epithelial cell survival

A20 (TNFAIP3) and ABIN-1 (TNIP1) are candidate susceptibility genes for inflammatory bowel disease and other autoimmune or inflammatory diseases, but it is unclear how these proteins interact in vivo to prevent disease. Here we show that intestinal epithelial cell (IEC)-specific deletion of either A...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Exp Med
Prif Awduron: Kattah, Michael G., Shao, Ling, Rosli, Yenny Y., Shimizu, Hiromichi, Whang, Michael I., Advincula, Rommel, Achacoso, Philip, Shah, Sanjana, Duong, Bao H., Onizawa, Michio, Tanbun, Priscilia, Malynn, Barbara A., Ma, Averil
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Rockefeller University Press 2018
Pynciau:
Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028510/
https://ncbi.nlm.nih.gov/pubmed/29930103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20180198
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg