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Centrosomal ALIX regulates mitotic spindle orientation by modulating astral microtubule dynamics

The orientation of the mitotic spindle (MS) is tightly regulated, but the molecular mechanisms are incompletely understood. Here we report a novel role for the multifunctional adaptor protein ALG‐2‐interacting protein X (ALIX) in regulating MS orientation in addition to its well‐established role in...

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Bibliografische gegevens
Gepubliceerd in:EMBO J
Hoofdauteurs: Malerød, Lene, Le Borgne, Roland, Lie‐Jensen, Anette, Eikenes, Åsmund Husabø, Brech, Andreas, Liestøl, Knut, Stenmark, Harald, Haglund, Kaisa
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028035/
https://ncbi.nlm.nih.gov/pubmed/29858227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201797741
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