Centrosomal ALIX regulates mitotic spindle orientation by modulating astral microtubule dynamics

The orientation of the mitotic spindle (MS) is tightly regulated, but the molecular mechanisms are incompletely understood. Here we report a novel role for the multifunctional adaptor protein ALG‐2‐interacting protein X (ALIX) in regulating MS orientation in addition to its well‐established role in...

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Udgivet i:EMBO J
Main Authors: Malerød, Lene, Le Borgne, Roland, Lie‐Jensen, Anette, Eikenes, Åsmund Husabø, Brech, Andreas, Liestøl, Knut, Stenmark, Harald, Haglund, Kaisa
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2018
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028035/
https://ncbi.nlm.nih.gov/pubmed/29858227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201797741
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