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Centrosomal ALIX regulates mitotic spindle orientation by modulating astral microtubule dynamics

The orientation of the mitotic spindle (MS) is tightly regulated, but the molecular mechanisms are incompletely understood. Here we report a novel role for the multifunctional adaptor protein ALG‐2‐interacting protein X (ALIX) in regulating MS orientation in addition to its well‐established role in...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:EMBO J
Egile Nagusiak: Malerød, Lene, Le Borgne, Roland, Lie‐Jensen, Anette, Eikenes, Åsmund Husabø, Brech, Andreas, Liestøl, Knut, Stenmark, Harald, Haglund, Kaisa
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028035/
https://ncbi.nlm.nih.gov/pubmed/29858227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201797741
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