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Centrosomal ALIX regulates mitotic spindle orientation by modulating astral microtubule dynamics

The orientation of the mitotic spindle (MS) is tightly regulated, but the molecular mechanisms are incompletely understood. Here we report a novel role for the multifunctional adaptor protein ALG‐2‐interacting protein X (ALIX) in regulating MS orientation in addition to its well‐established role in...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Malerød, Lene, Le Borgne, Roland, Lie‐Jensen, Anette, Eikenes, Åsmund Husabø, Brech, Andreas, Liestøl, Knut, Stenmark, Harald, Haglund, Kaisa
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028035/
https://ncbi.nlm.nih.gov/pubmed/29858227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201797741
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