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A mitotic SKAP isoform regulates spindle positioning at astral microtubule plus ends

The Astrin/SKAP complex plays important roles in mitotic chromosome alignment and centrosome integrity, but previous work found conflicting results for SKAP function. Here, we demonstrate that SKAP is expressed as two distinct isoforms in mammals: a longer, testis-specific isoform that was used for...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Kern, David M., Nicholls, Peter K., Page, David C., Cheeseman, Iain M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862331/
https://ncbi.nlm.nih.gov/pubmed/27138257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201510117
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