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A mitotic SKAP isoform regulates spindle positioning at astral microtubule plus ends

The Astrin/SKAP complex plays important roles in mitotic chromosome alignment and centrosome integrity, but previous work found conflicting results for SKAP function. Here, we demonstrate that SKAP is expressed as two distinct isoforms in mammals: a longer, testis-specific isoform that was used for...

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Vydáno v:J Cell Biol
Hlavní autoři: Kern, David M., Nicholls, Peter K., Page, David C., Cheeseman, Iain M.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862331/
https://ncbi.nlm.nih.gov/pubmed/27138257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201510117
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