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Centrosomal ALIX regulates mitotic spindle orientation by modulating astral microtubule dynamics

The orientation of the mitotic spindle (MS) is tightly regulated, but the molecular mechanisms are incompletely understood. Here we report a novel role for the multifunctional adaptor protein ALG‐2‐interacting protein X (ALIX) in regulating MS orientation in addition to its well‐established role in...

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Dades bibliogràfiques
Publicat a:EMBO J
Autors principals: Malerød, Lene, Le Borgne, Roland, Lie‐Jensen, Anette, Eikenes, Åsmund Husabø, Brech, Andreas, Liestøl, Knut, Stenmark, Harald, Haglund, Kaisa
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028035/
https://ncbi.nlm.nih.gov/pubmed/29858227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201797741
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