Amphiastral Mitotic Spindle Assembly in Vertebrate Cells Lacking Centrosomes

The role of centrosomes/centrioles during mitotic spindle assembly in vertebrates remains controversial. In cell-free extracts and experimentally derived acentrosomal cells, randomly oriented microtubules (MTs) self-organize around mitotic chromosomes and assemble anastral spindles [1, 2, 3]. Howeve...

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Main Authors: Hornick, Jessica E., Mader, Christopher C., Tribble, Emily K., Bagne, Cydney C., Vaughan, Kevin T., Shaw, Sidney L., Hinchcliffe, Edward H.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075362/
https://ncbi.nlm.nih.gov/pubmed/21439826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2011.02.049
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