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PKCε Controls Mitotic Progression by Regulating Centrosome Migration and Mitotic Spindle Assembly

To form a proper mitotic spindle, centrosomes must be duplicated and driven poleward in a timely and controlled fashion. Improper timing of centrosome separation and errors in mitotic spindle assembly may lead to chromosome instability, a hallmark of cancer. Protein Kinase C epsilon (PKCε) has recen...

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Detalhes bibliográficos
Publicado no:Mol Cancer Res
Main Authors: Martini, Silvia, Soliman, Tanya, Gobbi, Giuliana, Mirandola, Prisco, Carubbi, Cecilia, Masselli, Elena, Pozzi, Giulia, Parker, Peter J., Vitale, Marco
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5755688/
https://ncbi.nlm.nih.gov/pubmed/29021232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-17-0244
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