Mapping and Engineering Functional Domains of the Assembly-Activating Protein of Adeno-associated Viruses

Adeno-associated viruses (AAVs) encode a unique assembly-activating protein (AAP) within their genomes that is essential for capsid assembly. Studies to date have focused on establishing the role of AAP as a chaperone that mediates the stability, nucleolar transport, and assembly of AAV capsid prote...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Tse, Longping V., Moller-Tank, Sven, Meganck, Rita M., Asokan, Aravind
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2018
Fag:
Structure and Assembly
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6026743/
https://ncbi.nlm.nih.gov/pubmed/29695425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00393-18
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