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Properties of the Adeno-Associated Virus Assembly-Activating Protein

Adeno-associated virus (AAV) capsid assembly requires expression of the assembly-activating protein (AAP) together with capsid proteins VP1, VP2, and VP3. AAP is encoded by an alternative open reading frame of the cap gene. Sequence analysis and site-directed mutagenesis revealed that AAP contains t...

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Detalhes bibliográficos
Main Authors: Naumer, Matthias, Sonntag, Florian, Schmidt, Kristin, Nieto, Karen, Panke, Christian, Davey, Norman E., Popa-Wagner, Ruth, Kleinschmidt, Jürgen A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497687/
https://ncbi.nlm.nih.gov/pubmed/23015698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01675-12
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