GATA6 suppression enhances lung specification from human pluripotent stem cells

The transcription factor GATA6 has been shown to be important for lung development and branching morphogenesis in mouse models, but its role in human lung development is largely unknown. Here, we studied the role of GATA6 during lung differentiation using human pluripotent stem cells. We found that...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Main Authors: Liao, Chia-Min, Mukherjee, Somdutta, Tiyaboonchai, Amita, Maguire, Jean Ann, Cardenas-Diaz, Fabian L., French, Deborah L., Gadue, Paul
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2018
Fag:
Concise Communication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6025967/
https://ncbi.nlm.nih.gov/pubmed/29889101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI96539
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