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Highly efficient CRISPR/Cas9 mediated genome editing in human pluripotent stem cells

Human PSCs offer tremendous potential for both basic biology and cell-based therapies for a wide variety of diseases. The ability to manipulate the genome of these cells using the CRISPR/Cas9 technology has expanded this potential by providing a valuable tool to engineer or correct disease-associate...

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Detalhes bibliográficos
Publicado no:Curr Protoc Stem Cell Biol
Main Authors: Maguire, Jean Ann, Cardenas-Diaz, Fabian L., Gadue, Paul, French, Deborah L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6336498/
https://ncbi.nlm.nih.gov/pubmed/30358158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpsc.64
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