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CRISPR-Cas9 Based Genome Editing of Human Induced Pluripotent Stem Cells

Emergence of the CRISPR-Cas9 system has revolutionized the field of genome editing. Specifically, by introducing inexpensive reagents, that are relatively straightforward to design and validate, it is now possible to correct genetic variants or insert desired sequences at any location within the gen...

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Bibliographische Detailangaben
Veröffentlicht in:Curr Protoc Stem Cell Biol
Hauptverfasser: Giacalone, Joseph C., Sharma, Tasneem P., Burnight, Erin R., Fingert, John F., Mullins, Robert F., Stone, Edwin M., Tucker, Budd A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5846340/
https://ncbi.nlm.nih.gov/pubmed/29512106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpsc.46
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