Correction of NR2E3 Associated Enhanced S-cone Syndrome Patient-specific iPSCs using CRISPR-Cas9

Enhanced S-cone syndrome (ESCS) is caused by recessive mutations in the photoreceptor cell transcription factor NR2E3. Loss of NR2E3 is characterized by repression of rod photoreceptor cell gene expression, over-expansion of the S-cone photoreceptor cell population, and varying degrees of M- and L-c...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Genes (Basel)
Autori principali: Bohrer, Laura R., Wiley, Luke A., Burnight, Erin R., Cooke, Jessica A., Giacalone, Joseph C., Anfinson, Kristin R., Andorf, Jeaneen L., Mullins, Robert F., Stone, Edwin M., Tucker, Budd A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2019
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6523438/
https://ncbi.nlm.nih.gov/pubmed/30959774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes10040278
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi