CRISPR-CAS9 GENOME ENGINEERING: TREATING INHERITED RETINAL DEGENERATION

Gene correction is a valuable strategy for treating inherited retinal degenerative diseases, a major cause of irreversible blindness worldwide. Single gene defects cause the majority of these retinal dystrophies. Gene augmentation holds great promise if delivered early in the course of the disease,...

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Detalhes bibliográficos
Publicado no:Prog Retin Eye Res
Main Authors: Burnight, Erin R, Giacalone, Joseph C, Cooke, Jessica A, Thompson, Jessica R, Bohrer, Laura R, Chirco, Kathleen R, Drack, Arlene V, Fingert, John H, Worthington, Kristan S, Wiley, Luke A, Mullins, Robert F, Stone, Edwin M, Tucker, Budd A
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8210531/
https://ncbi.nlm.nih.gov/pubmed/29578069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.preteyeres.2018.03.003
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