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Comprehensive protocols for CRISPR/Cas9-based gene editing in human pluripotent stem cells

Application of the CRISPR/Cas9 system to edit the genomes of human pluripotent stem cells (hPSCs) has the potential to revolutionize hPSC-based disease modeling, drug screening, and transplantation therapy. Here, we aim to provide a single resource to enable groups, even those with limited experienc...

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Bibliografiska uppgifter
I publikationen:Curr Protoc Stem Cell Biol
Huvudupphovsmän: Santos, David P., Kiskinis, Evangelos, Eggan, Kevin, Merkle, Florian T.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4988528/
https://ncbi.nlm.nih.gov/pubmed/27532820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpsc.15
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