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Efficient CRISPR/Cas9-based Genome Engineering in Human Pluripotent Stem Cells

Human pluripotent stem cells (hPSCs) are rapidly emerging as a powerful tool for biomedical discovery. The advent of human induced pluripotent stem (hiPS) cells with human embryonic stem (hES) cell-like properties has led to hPSCs with disease-specific genetic backgrounds for in-vitro disease modeli...

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Bibliografiska uppgifter
I publikationen:Curr Protoc Hum Genet
Huvudupphovsmän: Kime, Cody, Mandegar, Mohammad A., Srivastava, Deepak, Yamanaka, Shinya, Conklin, Bruce R., Rand, Tim A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4726454/
https://ncbi.nlm.nih.gov/pubmed/26724721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/0471142905.hg2104s88
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