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GATA6 suppression enhances lung specification from human pluripotent stem cells

The transcription factor GATA6 has been shown to be important for lung development and branching morphogenesis in mouse models, but its role in human lung development is largely unknown. Here, we studied the role of GATA6 during lung differentiation using human pluripotent stem cells. We found that...

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Podrobná bibliografie
Vydáno v:J Clin Invest
Hlavní autoři: Liao, Chia-Min, Mukherjee, Somdutta, Tiyaboonchai, Amita, Maguire, Jean Ann, Cardenas-Diaz, Fabian L., French, Deborah L., Gadue, Paul
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6025967/
https://ncbi.nlm.nih.gov/pubmed/29889101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI96539
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