Single-Molecule Characterization of the Interactions between Extracellular Chaperones and Toxic α-Synuclein Oligomers

The aberrant aggregation of α-synuclein is associated with several human diseases, collectively termed the α-synucleinopathies, which includes Parkinson’s disease. The progression of these diseases is, in part, mediated by extracellular α-synuclein oligomers that may exert effects through several me...

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Gepubliceerd in:Cell Rep
Hoofdauteurs: Whiten, Daniel R., Cox, Dezerae, Horrocks, Mathew H., Taylor, Christopher G., De, Suman, Flagmeier, Patrick, Tosatto, Laura, Kumita, Janet R., Ecroyd, Heath, Dobson, Christopher M., Klenerman, David, Wilson, Mark R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cell Press 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6024880/
https://ncbi.nlm.nih.gov/pubmed/29924993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.05.074
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