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Optical Structural Analysis of Individual α‐Synuclein Oligomers

Small aggregates of misfolded proteins play a key role in neurodegenerative disorders. Such species have proved difficult to study due to the lack of suitable methods capable of resolving these heterogeneous aggregates, which are smaller than the optical diffraction limit. We demonstrate here an all...

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Detalles Bibliográficos
Publicado en:Angew Chem Int Ed Engl
Main Authors: Varela, Juan A., Rodrigues, Margarida, De, Suman, Flagmeier, Patrick, Gandhi, Sonia, Dobson, Christopher M., Klenerman, David, Lee, Steven F.
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5988047/
https://ncbi.nlm.nih.gov/pubmed/29342318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201710779
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