Optical Structural Analysis of Individual α‐Synuclein Oligomers

Small aggregates of misfolded proteins play a key role in neurodegenerative disorders. Such species have proved difficult to study due to the lack of suitable methods capable of resolving these heterogeneous aggregates, which are smaller than the optical diffraction limit. We demonstrate here an all...

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Bibliographic Details
Published in:Angew Chem Int Ed Engl
Main Authors: Varela, Juan A., Rodrigues, Margarida, De, Suman, Flagmeier, Patrick, Gandhi, Sonia, Dobson, Christopher M., Klenerman, David, Lee, Steven F.
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2018
Subjects:
Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5988047/
https://ncbi.nlm.nih.gov/pubmed/29342318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201710779
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