Optical Structural Analysis of Individual α‐Synuclein Oligomers

Small aggregates of misfolded proteins play a key role in neurodegenerative disorders. Such species have proved difficult to study due to the lack of suitable methods capable of resolving these heterogeneous aggregates, which are smaller than the optical diffraction limit. We demonstrate here an all...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Varela, Juan A., Rodrigues, Margarida, De, Suman, Flagmeier, Patrick, Gandhi, Sonia, Dobson, Christopher M., Klenerman, David, Lee, Steven F.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5988047/
https://ncbi.nlm.nih.gov/pubmed/29342318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201710779
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