Quantifying Co-Oligomer Formation by α-Synuclein

[Image: see text] Small oligomers of the protein α-synuclein (αS) are highly cytotoxic species associated with Parkinson’s disease (PD). In addition, αS can form co-aggregates with its mutational variants and with other proteins such as amyloid-β (Aβ) and tau, which are implicated in Alzheimer’s dis...

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Veröffentlicht in:ACS Nano
Hauptverfasser: Iljina, Marija, Dear, Alexander J., Garcia, Gonzalo A., De, Suman, Tosatto, Laura, Flagmeier, Patrick, Whiten, Daniel R., Michaels, Thomas C. T., Frenkel, Daan, Dobson, Christopher M., Knowles, Tuomas P. J., Klenerman, David
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2018
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6262461/
https://ncbi.nlm.nih.gov/pubmed/30371053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.8b03575
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