Assessment of the In Vivo Activity of SPR741 in Combination with Azithromycin against Multidrug-Resistant Enterobacteriaceae Isolates in the Neutropenic Murine Thigh Infection Model

SPR741 is a novel agent with structural similarity to polymyxins that is capable of potentiating the activities of various classes of antibiotics. Previously published studies indicated that although Enterobacteriaceae isolates had minimal susceptibilities to azithromycin (AZM), the in vitro antimic...

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Опубликовано в: :Antimicrob Agents Chemother
Главные авторы: Stainton, Sean M., Abdelraouf, Kamilia, Utley, Luke, Pucci, Michael J., Lister, Troy, Nicolau, David P.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2018
Предметы:
Experimental Therapeutics
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6021673/
https://ncbi.nlm.nih.gov/pubmed/29914941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00239-18
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