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Assessment of the In Vivo Activity of SPR741 in Combination with Azithromycin against Multidrug-Resistant Enterobacteriaceae Isolates in the Neutropenic Murine Thigh Infection Model

SPR741 is a novel agent with structural similarity to polymyxins that is capable of potentiating the activities of various classes of antibiotics. Previously published studies indicated that although Enterobacteriaceae isolates had minimal susceptibilities to azithromycin (AZM), the in vitro antimic...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Stainton, Sean M., Abdelraouf, Kamilia, Utley, Luke, Pucci, Michael J., Lister, Troy, Nicolau, David P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6021673/
https://ncbi.nlm.nih.gov/pubmed/29914941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00239-18
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