Nalaganje...
Hepatic deletion of p110α and p85α results in insulin resistance despite sustained IRS1-associated phosphatidylinositol kinase activity
Background: Class IA phosphatidylinositol-4,5-bisphosphate 3-kinase (PI3K) is an integral mediator of insulin signaling. The p110 catalytic and p85 regulatory subunits of PI3K are the products of separate genes, and while they come together to make the active heterodimer, they have opposing roles in...
Shranjeno v:
| izdano v: | F1000Res |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
F1000 Research Limited
2018
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6020741/ https://ncbi.nlm.nih.gov/pubmed/29983910 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.12418.2 |
| Oznake: |
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