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Direct association of p110 beta phosphatidylinositol 3-kinase with p85 is mediated by an N-terminal fragment of p110 beta.

Phosphatidylinositol (PI) 3-kinase is a heterodimeric enzyme of 85-kDa (p85) and 110-kDa (p110) subunits implicated in mitogenic signal transduction by virtue of its activation in cells transformed by diverse viral oncoproteins and treated with various growth factors. We have identified a domain in...

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Détails bibliographiques
Publié dans:Mol Cell Biol
Auteurs principaux: Hu, P, Schlessinger, J
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 1994
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC358625/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8139559/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.4.2577
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