SH2 domains of the p85 alpha subunit of phosphatidylinositol 3-kinase regulate binding to growth factor receptors.

The binding of cytoplasmic signaling proteins such as phospholipase C-gamma 1 and Ras GTPase-activating protein to autophosphorylated growth factor receptors is directed by their noncatalytic Src homology region 2 (SH2) domains. The p85 alpha regulatory subunit of phosphatidylinositol (PI) 3-kinase,...

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Autores principales: McGlade, C J, Ellis, C, Reedijk, M, Anderson, D, Mbamalu, G, Reith, A D, Panayotou, G, End, P, Bernstein, A, Kazlauskas, A
Formato: Artigo
Lenguaje:Inglês
Publicado: 1992
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC369531/
https://ncbi.nlm.nih.gov/pubmed/1372092
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