SH2 domains of the p85 alpha subunit of phosphatidylinositol 3-kinase regulate binding to growth factor receptors.

The binding of cytoplasmic signaling proteins such as phospholipase C-gamma 1 and Ras GTPase-activating protein to autophosphorylated growth factor receptors is directed by their noncatalytic Src homology region 2 (SH2) domains. The p85 alpha regulatory subunit of phosphatidylinositol (PI) 3-kinase,...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	McGlade, C J, Ellis, C, Reedijk, M, Anderson, D, Mbamalu, G, Reith, A D, Panayotou, G, End, P, Bernstein, A, Kazlauskas, A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369531/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1372092/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.3.991-997.1992
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