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Selective Molecular Antagonists of the Bronchiolar Epithelial NFκB-Bromodomain-Containing Protein 4 (BRD4) Pathway in Viral-induced Airway Inflammation
The mechanisms how the mammalian airway detects invading viral pathogens to trigger protective innate neutrophilic inflammation are incompletely understood. We observe that innate activation of the NFκB/RelA transcription factor indirectly activates atypical BRD4 histone acetyltransferase (HAT) acti...
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| Publicat a: | Cell Rep |
|---|---|
| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6020052/ https://ncbi.nlm.nih.gov/pubmed/29694891 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.03.106 |
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