BRD4 Couples NF-κB/RelA with Airway Inflammation and the IRF-RIG-I Amplification Loop in Respiratory Syncytial Virus Infection

The airway mucosa expresses protective interferon (IFN) and inflammatory cytokines in response to respiratory syncytial virus (RSV) infection. In this study, we examine the role of bromodomain containing 4 (BRD4) in mediating this innate immune response in human small airway epithelial cells. We obs...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Tian, Bing, Yang, Jun, Zhao, Yingxin, Ivanciuc, Teodora, Sun, Hong, Garofalo, Roberto P., Brasier, Allan R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Cellular Response to Infection
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5331805/
https://ncbi.nlm.nih.gov/pubmed/28077651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00007-17
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